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Tissue-specific mismatch repair protein expression: MSH3 is higher than MSH6 in multiple mouse tissues

Archive ouverte | Tomé, Stéphanie | CCSD

International audience

The mouse mismatch repair protein, MSH3, is a nucleoplasmic protein that aggregates into denser nuclear bodies under conditions of stress

Archive ouverte | Holt, Ian | CCSD

International audience. The mismatch repair protein, MSH3, together with MSH2, forms the MutSβ heterodimer which recognizes and repairs base pair mismatches and larger insertion/deletion loops in DNA. Lack of specif...

Tissue- and age-specific DNA replication patterns at the CTG/CAG-expanded human myotonic dystrophy type 1 locus

Archive ouverte | Cleary, John | CCSD

International audience. Myotonic dystrophy, caused by DM1 CTG/CAG repeat expansions, shows varying instability levels between tissues and across ages within patients. We determined DNA replication profiles at the DM...

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