Longitudinal study assessing the return of chloroquine susceptibility of Plasmodium falciparum in isolates from travellers returning from West and Central Africa, 2000–2011

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El Safadi, Dima | Cian, Amandine | Nourrisson, Céline | Pereira, Bruno | Morelle, Christelle | Bastien, Patrick | Bellanger, Anne-Pauline | Botterel, Françoise | Candolfi, Ermanno | Desoubeaux, Guillaume | Lachaud, Laurence | Morio, Florent | Pomares, Christelle | Rabodonirina, Meja | Wawrzyniak, Ivan | Delbac, Frédéric | Gantois, Nausicaa | Certad, Gabriela | Delhaes, Laurence | Poirier, Philippe | Viscogliosi, Eric | Gharbi, Myriam | Flegg, Jennifer | Hubert, Véronique | Kendjo, Eric | Metcalf, Jessica | Bertaux, Lionel | Guérin, Philippe | Le Bras, Jacques | Aboubaca, Ahmed | Agnamey, Patrice | Angoulvant, Adela | Barbut, Patricia | Basset, Didier | Belkadi, Ghania | Bellanger, Anne Pauline | Bemba, Dieudonné | Benoit-Vica, Françoise | Berry, Antoine | Bigel, Marie-Laure | Bonhomme, Julie | Bouchaud, Olivier | Bougnoux, Marie-Elisabeth | Bourée, Patrice | Bourgeois, Nathalie | Branger, Catherine | Bret, Laurent | Buret, Bernadette | Casalino, Enrique | Chevrier, Sylviane | Conquere de Monbrison, Frédérique | Cuisenier, Bernadette | Danis, Martin | Darde, Marie-Laure | de Gentile, Ludovic | Delarbre, Jean-Marie | Delaunay, Pascal | Delaval, Anne | Develoux, Michel | Dunand, Jean | Durand, Rémy | Eloy, Odile | Fauchet, Nathalie | Faugere, Bernard | Faye, Alber | Fenneteau, Odile | Flori, Pierre | Fontrouge, Madeleine | Garabedian, Chantal | Gayandrieu, Françoise | Godineau, Nadine | Houzé, Pascal | Houzé, Sandrine | Hurst, Jean-Pierre | Ichou, Houria | Lebuisson, Agathe | Lefevre, Magalie | Leguern, Anne-Sophie | Le Moal, Gwenaë | Lusina, Daniel | Machouart, Marie-Claude | Malvy, Denis | Matheron, Sophie | Maubon, Danièle | Mechali, Denis | Megarbane, Bruno | Menard, Guillaume | Millon, Laurence | Aiach, Muriel Mimoun | Minodier, Philippe | Nevez, Gilles | Parola, Philippe | Parzy, Daniel | Patey, Olivier | Patoz, Pierre | Penn, Pascale | Perignon, Alice | Picot, Stéphane | Pilo, Jean-Etienne | Poilane, Isabelle | Pons, Denis | Poupart, Marie | Pradines, Bruno | Raffenot, Didier | Rapp, Christophe | Receveur, Marie-Catherine | Sarfati, Claudine | Senghor, Yaye | Simon, Fabrice | Siriez, Jean-Yves | Taudon, Nicolas | Thellier, Marc | Thouvenin, Maxime | Toubas, Dominique

Edité par CCSD ; BioMed Central -

International audience. Chloroquine (CQ) was the main malaria therapy worldwide from the 1940s until the 1990s. Following the emergence of CQ-resistant Plasmodium falciparum, most African countries discontinued the use of CQ, and now promote artemisinin-based combination therapy as the first-line treatment. This change was generally initiated during the last decade in West and Central Africa. The aim of this study is to describe the changes in CQ susceptibility in this African region, using travellers returning from this region as a sentinel system.

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