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Bisphenol A exposure during gestation and lactation in mice: Sex-specific consequences on oligodendrocytes and myelination

Archive ouverte | Naffaa, Vanessa | CCSD

International audience. Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, is suspected of disturbing brain development through largely unknown cellular and molecular mechanisms. In the central nervo...

Neurotoxicity of endocrine disruptors : evaluation of the impact of bisphenol A on myelination by a global lipidomics approach. Neurotoxicité des perturbateurs endocriniens : évaluation de l'impact du bisphénol A sur la myélinisation par une approche lipidomique globale

Archive ouverte | Naffaa, Vanessa | CCSD

During development, the brain is exposed to a myriad of endocrine disruptors (EDCs) which, even at low doses, can interfere with many signaling pathways and thereby contribute to the development of neurodevelopmental disorders. Fe...

Epigenetic priming of immune/inflammatory pathways activation and abnormal activity of cell cycle pathway in a perinatal model of white matter injury

Archive ouverte | Schang, Anne-Laure | CCSD

International audience. Abstract Prenatal inflammatory insults accompany prematurity and provoke diffuse white matter injury (DWMI), which is associated with increased risk of neurodevelopmental pathologies, includi...

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