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Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma

Archive ouverte | Niogret, Julie | CCSD

International audience. Background: Predictive biomarkers of response to chemotherapy plus antiangiogenic for metastatic colorectal cancer (mCRC) are lacking. The objective of this study was to test the prognostic r...

Accumulation of MDSC and Th17 Cells in Patients with Metastatic Colorectal Cancer Predicts the Efficacy of a FOLFOX-Bevacizumab Drug Treatment Regimen

Archive ouverte | Limagne, Emeric | CCSD

International audience. Host immunity controls the development of colorectal cancer, and chemotherapy used to treat colorectal cancer is likely to recruit the host immune system at some level. Athough preclinical st...

Étude des lymphocytes Th9 humains dans les cancers du sein

Archive ouverte | Thibaudin, Marion | CCSD

International audience. ObjetLes cellules du système immunitaire présentes dans le microenvironnement tumoral contribuent au contrôle de la progression tumorale [1]. Les lymphocytes T CD4 de type Th9, cellules sécré...

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