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Desperately seeking a home marrow niche for T-cell acute lymphoblastic leukaemia

Archive ouverte | Calvo, Julien | CCSD

International audience

High CD44 expression and enhanced E-selectin binding identified as biomarkers of chemoresistant leukemic cells in human T-ALL

Archive ouverte | Calvo, Julien | CCSD

International audience. T-cell acute lymphoblastic leukemia (T-ALL) is a hematopoietic malignancy characterized by increased proliferation and incomplete maturation of T-cell progenitors, for which relapse is often ...

Bone marrow sites differently imprint dormancy and chemoresistance to T-cell acute lymphoblastic leukemia

Archive ouverte | Cahu, Xavier | CCSD

International audience. T-cell acute lymphoblastic leukemia (T-ALL) expands in various bonemarrow (BM) sites of the body. We investigated whether different BM sites could differently modulate T-ALL propagation using...

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