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Recombinant Nox4 cytosolic domain produced by a cell or cell-free base systems exhibits constitutive diaphorase activity.

Archive ouverte | Nguyen, Minh Vu Chuong | CCSD

International audience. The membrane protein NADPH (nicotinamide adenine dinucleotide phosphate) oxidase Nox4 constitutively generates reactive oxygen species differing from other NADPH oxidases activity, particular...

Concerted activities of nitric oxide synthases and NADPH oxidases in PLB-985 cells.

Archive ouverte | Verchier, Yann | CCSD

International audience. Oxidative stress is a metabolic situation used by immune cells to provide protection against infection. Under activation by threatening elements, phagocytes produce chemically toxic molecules...

NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.

Archive ouverte | Lardy, Bernard | CCSD

International audience. Membrane-associated NADPH oxidase complexes catalyse the production of the superoxide anion radical from oxygen and NADPH. In mammalian systems, NADPH oxidases form a family of at least seven...

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