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TRIM33 deficiency in monocytes and macrophages impairs resolution of colonic inflammation

Archive ouverte | Petit, Vanessa | CCSD

International audience

TRIM33 switches off $Ifnb1$ gene transcription during the late phase of macrophage activation

Archive ouverte | Ferri, Federica | CCSD

International audience. Despite its importance during viral or bacterial infections, transcriptional regulation of the interferon-β gene (Ifnb1) in activated macrophages is only partially understood. Here we report ...

Macrophage production and activation are dependent on TRIM33

Archive ouverte | Gallouet, Anne-Sophie | CCSD

The tripartite motif (TRIM) family of proteins plays important roles in innate immunity and antimicrobial infection. None of these proteins has been shown to directly regulate transcription of genes in monocyte/macrophage except T...

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