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The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells

Archive ouverte | Claude-Taupin, Aurore | CCSD

International audience. Abstract Shear stress generated by urinary fluid flow is an important regulator of renal function. Its dysregulation is observed in various chronic and acute kidney diseases. Previously, we d...

The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells

Archive ouverte | Claude-Taupin, Aurore | CCSD

International audience. Shear stress generated by urinary fluid flow is an important regulator of renal function. Its dysregulation is observed in various chronic and acute kidney diseases. Previously, we demonstrat...

Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

Archive ouverte | Orhon, Idil | CCSD

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