Afficher la couverture 'The Polycomb landscape in mouse development | Richard Albert, Julien' en grand format
/5

0 avis

The Polycomb landscape in mouse development

Archive ouverte

Richard Albert, Julien | Greenberg, Maxim

Edité par CCSD ; Nature Publishing Group -

International audience. Polycomb-group proteins assemble into two primary complexes-Polycomb repressive complex (PRC) 1 and 2-that safeguard cell fate by repressing gene transcription. Two new studies explore the PRC1 landscape during the transition from gametes to embryos in mice, thus providing insight into the intergenerational transmission of epigenetic information and gene regulation dynamics as embryos prepare for gastrulation.

Suggestions

Du même auteur

Non-canonical imprinting in the spotlight

Archive ouverte | Albert, Julien Richard | CCSD

International audience. ABSTRACT Classical genomic imprints are regulated by parent-specific DNA methylation levels inherited from the gametes in mammals. Imprints control gene expression in a parent-of-origin manne...

Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs

Archive ouverte | Manceau, Line | CCSD

International audience. The hallmarks of the alveolar subclass of rhabdomyosarcoma are chromosomal translocations that generate chimeric PAX3-FOXO1 or PAX7-FOXO1 transcription factors. Overexpression of either PAX-F...

Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs

Archive ouverte | Manceau, Line | CCSD

Abstract The hallmarks of the alveolar subclass of rhabdomyosarcoma are chromosomal translocations that generate chimeric PAX3-FOXO1 or PAX7-FOXO1 transcription factors. Both PAX-FOXO1s result in related cell transformation in ani...

Chargement des enrichissements...