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Brain network remodelling reflects tau-related pathology prior to memory deficits in Thy-Tau22 mice

Archive ouverte | Degiorgis, Laetitia | CCSD

International audience. In Alzheimer's disease, the tauopathy is known as a major mechanism responsible for the development of cognitive deficits. Early biomarkers of such affectations for diagnosis/stratification a...

Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

Archive ouverte | Mechling, Anna E. | CCSD

Connectome genetics seeks to uncover how genetic factors shape brain functional connectivity; however, the causal impact of a single gene's activity on whole-brain networks remains unknown. We tested whether the sole targeted dele...

Common functional networks in the mouse brain revealed by multi-centre resting-state fMRI analysis

Archive ouverte | Grandjean, Joanes | CCSD

International audience. Preclinical applications of resting-state functional magnetic resonance imaging (rsfMRI) offer the possibility to non-invasively probe whole-brain network dynamics and to investigate the dete...

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