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SPINE bioinformatics and data-management aspects of high-throughput structural biology.

Archive ouverte | Albeck, S. | CCSD

International audience. SPINE (Structural Proteomics In Europe) was established in 2002 as an integrated research project to develop new methods and technologies for high-throughput structural biology. Development a...

First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value.

Archive ouverte | Banci, L. | CCSD

International audience. The EC 'Structural Proteomics In Europe' contract is aimed specifically at the atomic resolution structure determination of human protein targets closely linked to health, with a focus on can...

Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE.

Archive ouverte | Alzari, Pedro Maria | CCSD

International audience. The implementation of high-throughput (HTP) cloning and expression screening in Escherichia coli by 14 laboratories in the Structural Proteomics In Europe (SPINE) consortium is described. Clo...

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