Afficher la couverture 'Target highlights in CASP14 : Analysis of models by structure providers | Alexander, Leila' en grand format
/5

0 avis

Target highlights in CASP14 : Analysis of models by structure providers

Archive ouverte

Alexander, Leila | Lepore, Rosalba | Kryshtafovych, Andriy | Adamopoulos, Athanassios | Alahuhta, Markus | Arvin, Ann | Bomble, Yannick | Böttcher, Bettina | Breyton, Cécile | Chiarini, Valerio | Chinnam, Naga Babu | Chiu, Wah | Fidelis, Krzysztof | Grinter, Rhys | Gupta, Gagan | Hartmann, Marcus | Hayes, Christopher | Heidebrecht, Tatjana | Ilari, Andrea | Joachimiak, Andrzej | Kim, Youngchang | Linares, Romain | Lovering, Andrew | Lunin, Vladimir | Lupas, Andrei | Makbul, Cihan | Michalska, Karolina | Moult, John | Mukherjee, Prasun | Nutt, William Sam | Oliver, Stefan | Perrakis, Anastassis | Stols, Lucy | Tainer, John | Topf, Maya | Tsutakawa, Susan | Valdivia-Delgado, Mauricio | Schwede, Torsten

Edité par CCSD ; Wiley -

International audience. The biological and functional significance of selected Critical Assessment of Techniques for Protein Structure Prediction 14 (CASP14) targets are described by the authors of the structures. The authors highlight the most relevant features of the target proteins and discuss how well these features were reproduced in the respective submitted predictions. The overall ability to predict three-dimensional structures of proteins has improved remarkably in CASP14, and many difficult targets were modeled with impressive accuracy. For the first time in the history of CASP, the experimentalists not only highlighted that computational models can accurately reproduce the most critical structural features observed in their targets, but also envisaged that models could serve as a guidance for further studies of biologically-relevant properties of proteins.

Suggestions

Du même auteur

Target highlights in CASP13: Experimental target structures through the eyes of their authors

Archive ouverte | Lepore, Rosalba | CCSD

International audience. The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural feature...

Protein target highlights in CASP15 : Analysis of models by structure providers

Archive ouverte | Alexander, Leila, T. | CCSD

International audience. We present an in‐depth analysis of selected CASP15 targets, focusing on their biological and functional significance. The authors of the structures identify and discuss key protein features a...

Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016)

Archive ouverte | Kryshtafovych, Andriy | CCSD

International audience. The functional and biological significance of the selected CASP12 targets are described by the authors of the structures. The crystallographers discuss the most interesting structural feature...

Chargement des enrichissements...