Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases

0 avis

Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases

Archive ouverte

Edité par CCSD ; Wiley -

International audience. Clinical heterogeneity, a hallmark of systemic autoimmune diseases, impedes early diagnosis and effective treatment, issues that may be addressed if patients could be classified into groups defined by molecular pattern. This study was undertaken to identify molecular clusters for reclassifying systemic autoimmune diseases independently of clinical diagnosis.

Langue: en

Consulter en ligne

Consulter le document

Suggestions

Du même auteur

A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome. A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome: Identification of altered cell signaling pathways using proteomic profiling in stable and progressive chronic lymphocytic leukemia.

Archive ouverte | Soret, Perrine | CCSD

International audience. Abstract There is currently no approved treatment for primary Sjögren’s syndrome, a disease that primarily affects adult women. The difficulty in developing effective therapies is -in part- b...

Integrative epigenomics in Sjögren´s syndrome reveals novel pathways and a strong interaction between the HLA, autoantibodies and the interferon signature

Archive ouverte | Teruel, María | CCSD

International audience. Abstract Primary Sjögren’s syndrome (SS) is a systemic autoimmune disease characterized by lymphocytic infiltration and damage of exocrine salivary and lacrimal glands. The etiology of SS is ...

Transcriptome and Methylome Integrative Molecular Analysis Uncovers a New Systemic Autoimmune Disease Classification

Archive ouverte | Barturen, Guillermo | CCSD

International audience

Chargement des enrichissements...

Syracuse