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Structural basis of client specificity in mitochondrial membrane-protein chaperones

Archive ouverte | Sučec, Iva | CCSD

Chaperones are essential for assisting protein folding, and for transferring poorly soluble proteins to their functional locations within cells. Hydrophobic interactions drive promiscuous chaperone–client binding, but our understa...

Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space

Archive ouverte | Weinhäupl, Katharina | CCSD

International audience. The exchange of metabolites between the mitochon- drial matrix and the cytosol depends on b-barrel channels in the outer membrane and a-helical carrier proteins in the inner membrane. The ess...

Architecture and assembly dynamics of the essential mitochondrial chaperone complex TIM9·10·12

Archive ouverte | Weinhäupl, Katharina | CCSD

International audience

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