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Assembling the Current Pieces: The Puzzle of RNA-Mediated Regulation in Staphylococcus aureus

Archive ouverte | Barrientos, Laura | CCSD

The success of the major opportunistic human Staphylococcus aureus relies on the production of numerous virulence factors, which allow rapid colonization and dissemination in any tissues. Indeed, regulation of its virulence is mul...

An unprecedented small RNA-riboswitch interaction controls expression of a bifunctional pump that is essential forStaphylococcus aureusinfection

Archive ouverte | González-Espinoza, Gabriela | CCSD

Maintaining manganese and iron homeostasis is critical for the human pathogenStaphylococcus aureus. To counteract metal-based host defense strategies (e.g., nutritional immunity, metal poisoning), S. aureus uses a combination of m...

Navigation through the twists and turns of RNA sequencing technologies: Application to bacterial regulatory RNAs

Archive ouverte | Desgranges, Emma | CCSD

Discovered in the 1980s, small regulatory RNAs (sRNAs) are now considered key actors in virtually all aspects ofbacterial physiology and virulence. Together with transcriptional and translational regulatory proteins, theyintegrate...

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