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Increased macroH2A1.1 Expression Correlates with Poor Survival of Triple-Negative Breast Cancer Patients
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Edité par CCSD ; Public Library of Science -
International audience. Epithelial-Mesenchymal Transition (EMT) features appear to be key events in development and progression of breast cancer. Epigenetic modifications contribute to the establishment and maintenance of cancer subclasses, as well as to the EMT process. Whether histone variants contribute to these transformations is not known. We investigated the relative expression levels of histone macroH2A1 splice variants and correlated it with breast cancer status/prognosis/types.
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