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Immunological characterization of HIV-2 and HIV-1 human immunodeficiency virus reservoirs in immunocompetent cells and study of innate and intrinsic immunity parameters. Caractérisation immunologique des réservoirs des virus de l’immunodéficience humaine VIH-2 et VIH-1 dans les cellules immunocompétentes et étude des paramètres de l’immunité innée et intrinsèque

Archive ouverte | Diallo, Mariama Sadjo | CCSD

HIV-2 and HIV-1 differ in pathogenicity. To better understand the mechanisms of HIV- 2 low pathogenicity and replication potential, we studied immune and virologic characteristics of HIV-2 reservoirs of infected patients (cohort A...

Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection

Archive ouverte | Samri, Assia | CCSD

International audience. The low pathogenicity and replicative potential of HIV-2 are still poorly understood. We investigated whether HIV-2 reservoirs might follow the peculiar distribution reported in models of att...

Initiating antiretroviral treatment early in infancy has long-term benefits on the HIV reservoir in late childhood and adolescence

Archive ouverte | Avettand-Fenoel, Véronique | CCSD

International audience. BackgroundEarly combined antiretroviral therapy (cART) limits the total HIV-DNA load in children. However, data on its impact in older children and adolescents remain scarce. This study aims ...

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