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Crystal structure of the N-terminal domain of the trypanosome flagellar protein BILBO1 reveals a ubiquitin fold with a long structured loop for protein binding

Archive ouverte | Vidilaseris, Keni | CCSD

International audience. Trypanosoma brucei is a protist parasite causing sleeping sickness and nagana in sub-Saharan Africa. T. brucei has a single flagellum whose base contains a bulblike invagination of the plasma...

Structural and functional studies of the first tripartite protein complex at the Trypanosoma brucei flagellar pocket collar

Archive ouverte | Isch, Charlotte | CCSD

International audience. The flagellar pocket (FP) is the only endo-and exocytic organelle in most trypanosomes and, as such, is essential throughout the life cycle of the parasite. The neck of the FP is maintained e...

Interaction between the flagellar pocket collar and the hook complex via a novel microtubule-binding protein in Trypanosoma brucei

Archive ouverte | Albisetti, Anna | CCSD

International audience. Trypanosoma brucei belongs to a group of unicellular, flagellated parasites that are responsible for human African trypanosomiasis. An essential aspect of parasite pathogenicity is cytoskelet...

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