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Principles of chromosome organization for meiotic recombination. Organisation des chromosomes méiotiques pour la recombinaison

Archive ouverte | Biot, Mathilde | CCSD

International audience. In meiotic cells, chromosomes are organized as chromatin loop arrays anchored to a protein axis. This organization is essential to regulate meiotic recombination, from DNA double-strand break...

PRDM9 activity depends on HELLS and promotes local 5-hydroxymethylcytosine enrichment

Archive ouverte | Imai, Yukiko | CCSD

International audience. Meiotic recombination starts with the formation of DNA double-strand breaks (DSBs) at specific genomic locations that correspond to PRDM9-binding sites. The molecular steps occurring from PRD...

Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes

Archive ouverte | Papanikos, Frantzeskos | CCSD

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