Syracuse

The Putative Cofactor TIF1 Is a Protein Kinase That Is Hyperphosphorylated upon Interaction with Liganded Nuclear Receptors*

Archive ouverte | Fraser, Robert, A | CCSD

International audience. Ligand-induced gene activation by nuclear receptors (NRs) is a complex process requiring dissociation of corepressors and recruitment of coactivators. The putative transcriptional intermediar...

The bromodomain revisited

Archive ouverte | Jeanmougin, François | CCSD

hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II

Archive ouverte | Bertolotti, Anne | CCSD

TFIID is the main sequence-specific DNA-binding component of the RNA polymerase II (Pol II) transcriptional machinery. It is a multiprotein complex composed of the TATA-binding protein (TBP) and TBP-associated factors (TAF(II)s). ...