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Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer

Archive ouverte | Goehrig, Delphine | CCSD

International audience. Objective Pancreatic cancer is associated with an abundant stromal reaction leading to immune escape and tumour growth. This massive stroma drives the immune escape in the tumour. We aimed to...

Inhibition of activin signalling reduces the growth of LβT2 gonadotroph pituitary tumours in mouse

Archive ouverte | Ziverec, Audrey | CCSD

International audience. Pituitary tumours are benign neoplasms that derive from hormone-producing cells of the pituitary gland. While medical treatments have emerged for most subtypes, gonadotroph tumours that expre...

Immune Landscape of Pituitary Tumors Reveals Association Between Macrophages and Gonadotroph Tumor Invasion

Archive ouverte | Principe, Moitza | CCSD

International audience. Abstract Purpose Pituitary neuroendocrine tumors (PitNETs) are frequent intracranial neoplasms that present heterogenic characteristics. Little is known about the immune cell network that exi...

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