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Specific modulation of 28S_Um2402 rRNA 2′-O-ribose methylation as a novel epitranscriptomic marker of ZEB1-induced epithelial–mesenchymal transition in different mammary cell contexts

Archive ouverte | Morin, Chloé | CCSD

International audience. The epithelial–mesenchymal transition (EMT) is a dynamic transdifferentiation of epithelial cells into mesenchymal cells. EMT programs exhibit great diversity, based primarily on the distinct...

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Archive ouverte | Paraqindes, Hermes | CCSD

International audience. Background High-grade adult-type diffuse gliomas (HGGs) constitute a heterogeneous group of aggressive tumors that are mostly incurable. Recent advances highlighting the contribution of ribos...

Intricate ribosome composition and translational reprogramming in epithelial–mesenchymal transition

Archive ouverte | Morin, Chloé | CCSD

International audience. Epithelial–mesenchymal transition (EMT) involves profound changes in cell morphology, driven by transcriptional and epigenetic reprogramming. However, evidence suggests that translation and r...

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