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In vivo electrophysiological validation of DREADD‐based modulation of pallidal neurons in the non‐human primate

Archive ouverte | Deffains, Marc | CCSD

International audience. Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are widely used in rodents to manipulate neuronal activity and establish causal links between structure and function. Thei...

Acute Striato-Cortical Synchronization Induces Focal Motor Seizures in Primates

Archive ouverte | Aupy, Jerome | CCSD

International audience. Objective: Whether the basal ganglia are involved in the cortical synchronization during focal seizures is still an open question. In the present study, we proposed to synchronize cortico-str...

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Archive ouverte | Arotcarena, Marie-Laure | CCSD

International audience. Adeno-associated virus (AAV) vectors are increasingly used as an effective and safe approach to deliver genetic material to the central nervous system (CNS). The AAV9-derived variants, AAV-PH...

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