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A molecular mechanism for the topographic alignment of convergent neural maps.

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Savier, Élise | Eglen, Stephen J | Bathélémy, Amélie | Perraut, Martine | Pfrieger, Frank | Lemke, Greg | Reber, Michael

Edité par CCSD ; eLife Sciences Publication -

Sensory processing requires proper alignment of neural maps throughout the brain. In the superficial layers of the superior colliculus of the midbrain, converging projections from retinal ganglion cells and neurons in visual cortex must be aligned to form a visuotopic map, but the basic mechanisms mediating this alignment remain elusive. In a new mouse model, ectopic expression of ephrin-A3 (

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