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Lactococcus lactis ZitR Is a Zinc-Responsive Repressor Active in the Presence of Low, Nontoxic Zinc Concentrations In Vivo

Archive ouverte | Llull, Daniel, D. | CCSD

In the family Streptococcaceae, the genes encoding zinc ABC uptake systems (called zit or adc) are regulated by a coencoded MarR family member (i.e., ZitR or AdcR), whereas in the great majority of bacteria, these genes are regula...

Discovery of new type I toxin–antitoxin systems adjacent to CRISPR arrays in Clostridium difficile

Archive ouverte | Maikova, Anna | CCSD

International audience. Clostridium difficile, a major human enteropathogen, must cope with foreign DNA invaders and multiple stress factors inside the host. We have recently provided an experimental evidence of def...

Biophysical and structural characterization of a zinc-responsive repressor of the MarR superfamily

Archive ouverte | Fernández Varela, Paloma | CCSD

The uptake of zinc, which is vital in trace amounts, is tightly controlled in bacteria. For this control, bacteria of the Streptococcaceae group use a Zn(II)-binding repressor named ZitR in lactococci and AdcR in streptococci, whi...

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