The double-stranded RNA Bluetongue virus induces type I IFN in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.
The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.
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| Ruscanu, Suzana | CCSD
International audience.
Dendritic cells (DCs), especially plasmacytoid DCs (pDCs), produce large amounts of alpha/beta interferon (IFN-α/β) upon infection with DNA or RNA viruses, which has impacts on the physiopath...
Innate immune response to bluetongue virus in sheep dendritic cells for the control of viral pathogenesis and immunity.