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Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway.

Archive ouverte | Youl, E. | CCSD

International audience. BACKGROUND AND PURPOSE: Quercetin lowers plasma glucose, normalizes glucose tolerance tests and preserves pancreatic β-cell integrity in diabetic rats. However, its mechanism of action has ne...

Chicoric acid is an anti-oxidant molecule stimulating AMP Kinase, PGC-1alpha expression and mitochondrial activity in a model of skeletal muscular cells

Archive ouverte | Schlernitzauer, A. | CCSD

Chicoric acid is an anti-oxidant molecule stimulating AMP Kinase, PGC-1alpha expression and mitochondrial activity in a model of skeletal muscular cells. 8. Congrès de Physiologie, de Pharmacologie et de Thérapeutique

Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells

Archive ouverte | Bardy, G. | CCSD

International audience. Background and Purpose: Quercetin is a natural polyphenolic flavonoid that displays anti‐diabetic properties in vivo. Its mechanism of action on insulin‐secreting beta cells is poorly documen...

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