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Detection of G Protein-Coupled Receptor Complexes in Postmortem Human Brain by Proximity Ligation Assay

Archive ouverte | Zhu, Ying | CCSD

International audience. Combining immunological and molecular biological methods, the antibody-based proximity ligation assay (PLA) has been used for more than a decade to detect and quantify protein-protein interac...

Evidence for limited D1 and D2 receptor coexpression and colocalization within the dorsal striatum of the neonatal mouse

Archive ouverte | Biezonski, Dominik K. | CCSD

International audience. The striatum is the major input nucleus of the basal ganglia involved in reward processing, goal-directed behaviors, habit learning, and motor control. The striatum projects to the basal gang...

Detecting G protein-coupled receptor complexes in postmortem human brain with proximity ligation assay and a Bayesian classifier

Archive ouverte | Zhu, Ying | CCSD

International audience. Despite the controversy regarding the existence and physiological relevance of class A G protein-coupled receptor dimerization, there is substantial evidence for functional interactions betwe...

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