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Maternal Obesity Influences Placental Nutrient Transport, Inflammatory Status, and Morphology in Human Term Placenta

Archive ouverte | Nogues, Perrine | CCSD

International audience. Abstract Context Maternal obesity has a significant impact on placental development. However, this impact on the placenta’s structure and function (ie, nutrient transport and hormone and cyto...

Maternal obesity influences expression and DNA methylation of the adiponectin and leptin systems in human third-trimester placenta

Archive ouverte | Nogues, Perrine | CCSD

International audience. Background It is well established that obesity is associated with dysregulation of the ratio between the two major adipokines leptin and adiponectin. Furthermore, it was recently reported tha...

New model of human placental co-culture to evaluate the effects of food contaminants on placental barrier

Archive ouverte | Leconte, Camille | CCSD

The placenta, located at the interface between the maternal and the fetal sides, playsa crucial role in nutrient exchanges, endocrine function and immunity. This organ issensitive to maternal environment (nutrition, metabolism, po...

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