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Synchrotron radiation infrared microspectroscopy to assess the activity of vancomycin against endocarditis vegetation bacteria

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Batard, Eric | Jamme, Frederic | Montassier, Emmanuel | Bertrand, Dominique | Caillon, Jocelyne | Potel, Gilles | Dumas, Paul

Edité par CCSD ; Elsevier -

International audience. Infrared microspectroscopy was used to show that vancomycin alters infrared spectra of endocarditis vegetation bacteria, and that vancomycin effects on bacterial biochemical contents are unevenly distributed between peripheral and central areas of bacterial masses. Infrared microspectroscopy is useful to study the activity of antibacterial agents against bacteria in tissues. (C) 2011 Elsevier B.V. All rights reserved.

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