Clinical predictive criteria associated with live birth following elective single embryo transfer

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Sifer, Christophe | Herbemont, Charlene | Adda-Herzog, Elodie | Sermondade, Nathalie | Dupont, Charlotte, C. | Cedrin-Durnerin, Isabelle | Poncelet, Christophe | Levy, Rachel | Grynberg, Michael | Hugues, Jean-Noel

Edité par CCSD ; Elsevier -

International audience. Objective: We aimed to define clinical criteria from the patients related to the occurrence of live birth in case of elective single embryo transfer (eSET). Study design: We analyzed retrospectively 409 eSET at day 2/3 between March 2005 and July 2012, proposed in case of (i) woman's age <37 years, (ii) first/second IVFO cycle, (iii) >= 2 good quality embryos obtained (3-5/6-10 blastomeres at day 2/3 and <20% fragmentation), including one top embryo (4/8 cells). In all, 124/409 live births (30.3%) were obtained, separating patients into groups of women who had birth or not. Different clinical parameters of interest were compared between each group, using appropriate statistical tests at p < 0.05 significance level. Results: By comparing Body Mass Index (BMI), we report a statistically higher BMI among women who did not deliver (24.6 vs. 23.4 kg/m(2); p = 0.014). Using an analysis by BMI categories, we also precise a threshold of BMI >= 30 kg/m(2), negatively associated with the occurrence of live birth. Conclusion: BMI appears to be the only clinical parameter statistically associated with delivery following eSET strategy in a good prognosis infertile population. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

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