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Accelerated arterial stiffening and gene expression profile of the aorta in patients with coronary artery disease.

Archive ouverte | Fassot, Céline | CCSD

BACKGROUND: Hypertension and chronic renal failure (CRF) are considered models of accelerated arterial stiffening. Arterial stiffness increases further when CRF is associated with hypertension. We hypothesized that, in patients wi...

In utero exposure to maternal diabetes impairs vascular expression of prostacyclin receptor in rat offspring.

Archive ouverte | Duong van Huyen, Jean-Paul | CCSD

International audience. OBJECTIVE: To evaluate modifications of arterial structure, gene expression, and function in our model of rats exposed to maternal diabetes. RESEARCH DESIGN AND METHODS: Morphometric analyses...

Large Artery Stiffening and Remodeling Are Independently Associated With All-Cause Mortality and Cardiovascular Events in Chronic Kidney Disease

Archive ouverte | Karras, Alexandre | CCSD

International audience. Chronic kidney disease, even at moderate stages, is characterized by a high incidence of cardiovascular events. Subclinical damage to large arteries, such as increased arterial stiffness and ...

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