Suggestions

Du même auteur

Characterization and inhibition of aminopeptidase A by α-mercapto-β-amino acyl dipeptides

Archive ouverte | David, Christelle | CCSD

International audience

Identification of threonine 348 as a residue involved in aminopeptidase A substrate specificity.

Archive ouverte | Claperon, Cédric | CCSD

International audience. Aminopeptidase A (APA; EC 3.4.11.7) is a membrane-bound zinc metalloprotease cleaving in the brain the N-terminal aspartyl residue of angiotensin II to generate angiotensin III, which exerts ...

Investigation of Subsite Preferences in Aminopeptidase A (EC 3.4.11.7) Led to the Design of the First Highly Potent and Selective Inhibitors of This Enzyme

Archive ouverte | David, Christelle | CCSD

International audience. The study of the physiological roles of the membrane-bound zinc-aminopeptidase A (glutamyl aminopeptidase, EC 3.4.11.7) needs the design of efficient and selective inhibitors of this enzyme. ...

Chargement des enrichissements...