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Study of the selective enzymatic acylation of multifunctional compounds : Application to pseudo-ceramide synthesis. Etude de l'acylation sélective de composés multifonctionnels par voie enzymatique : Application à la synthèse de pseudo-céramides

Archive ouverte | Le Joubioux, Florian | CCSD

Ceramides are lipids from the sphingolipide class derived from the N-acylation of a sphingoid base from a fatty acid. These lipids and their analogs are compounds of interest used as active components in pharmaceutical and cosmeti...

Semi-pilot scale-up of a continuous packed-bed bioreactor system developed for the lipase-catalyzed production of pseudo-ceramides

Archive ouverte | Le Joubioux, Florian | CCSD

International audience. Ceramides are sphingolipid compounds that are very attractive as active components in both the pharmaceutical and the cosmetic industries. In this study, the synthesis of 1-O,3-N-diacyl 3-am...

Continuous lipase-catalyzed production of pseudo-ceramides in a packed-bed bioreactor

Archive ouverte | Le Joubioux, Florian | CCSD

International audience. Ceramides are spingolipid compounds that are very attractive as active components in both the phar-maceutical and the cosmetic industries. In this study, the synthesis of ceramide analogs, th...

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