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Deep Learning Improves Macromolecule Identification in 3D Cellular Cryo-Electron Tomograms

Archive ouverte | Moebel, Emmanuel | CCSD

International audience. Cryogenic electron tomography (cryo-ET) visualizes the 3D spatial distribution of macromolecules at nanometer resolution inside native cells. However, automated identification of macromolecul...

Prediction of protein assemblies, the next frontier: The CASP14‐CAPRI experiment

Archive ouverte | Lensink, Marc | CCSD

International audience. We present the results for CAPRI Round 50, the 4th joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of 12 targets, including 6 dimers, 3 trimers, and 3 high...

Community-wide evaluation of methods for predicting the effect of mutations on protein-protein interactions

Archive ouverte | Moretti, Rocco | CCSD

International audience. Community-wide blind prediction experiments such as CAPRI and CASP provide an objective measure of the current state of predictive methodology. Here we describe a community-wide assessment of...

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