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A unique cerebellar pattern of microglia activation in a mouse model of encephalopathy of prematurity

Archive ouverte | Klein, Luisa | CCSD

International audience. Abstract Preterm infants often show pathologies of the cerebellum, which are associated with impaired motor performance, lower IQ and poor language skills at school ages. Using a mouse model ...

Key roles of glial cells in the encephalopathy of prematurity

Archive ouverte | van Steenwinckel, Juliette | CCSD

International audience. Across the globe, approximately one in 10 babies are born preterm, that is, before37 weeks of a typical 40 weeks of gestation. Up to 50% of preterm born infantsdevelop brain injury, encephalo...

Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain

Archive ouverte | van Steenwinckel, Juliette | CCSD

International audience. Microglia of the developing brain have unique functional properties but how their activation states are regulated is poorly understood. Inflammatory activation of microglia in the still-devel...

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