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Profiling of phosphoinositide molecular species in human and mouse platelets identifies new species increasing following stimulation

Archive ouverte | Mujalli, Abdulrahman | CCSD

International audience

Impact of PI3Kα (Phosphoinositide 3-Kinase Alpha) Inhibition on Hemostasis and Thrombosis

Archive ouverte | Laurent, Pierre-Alexandre | CCSD

International audience. Objective— PI3Kα (phosphoinositide 3-kinase alpha) is a therapeutic target in oncology, but its role in platelets and thrombosis remains ill characterized. In this study, we have analyzed the...

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Archive ouverte | Vardon Bounes, Fanny | CCSD

International audience. Blood platelets are the first line of defense against hemorrhages and are also strongly involved in the processes of arterial thrombosis, a leading cause of death worldwide. Besides their wel...

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