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Tissue-nonspecific alkaline phosphatase is an anti-inflammatory nucleotidase

Archive ouverte | Bessueille, Laurence | CCSD

International audience. Tissue-nonspecific alkaline phosphatase (TNAP) is necessary for skeletal mineralization by its ability to hydrolyze the mineralization inhibitor inorganic pyrophosphate (PPi), which is mainly...

Chronic recurrent multifocal osteomyelitis in children with hypophosphatasia explained by anti-inflammatory nucleotidase activity of tissue nonspecific alkaline phosphatase in mesenchymal and hematopoietic cells

Archive ouverte | Bessueille, Laurence | CCSD

International audience

Alkaline phosphatase multi-tasks in the brain

Archive ouverte | Fonta, C | CCSD

International audience. Introduction: There are several genes for alkaline phosphatase (AP). One of them codes for TNAP (Tissue Non-specific Alkaline Phosphatase). It is a ubiquitous ectoenzyme located in different ...

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