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TLR-4 engagement of dendritic cells confers a BST-2/tetherin-mediated restriction of HIV-1 infection to CD4+ T cells across the virological synapse

Archive ouverte | Blanchet, Fabien P. | CCSD

International audience. Background : Dendritic cells and their subsets, located at mucosal surfaces, are among the first immune cells toencounter disseminating pathogens. The cellular restriction factor BST-2/tether...

Quantitative Multicolor Super-Resolution Microscopy Reveals Tetherin HIV-1 Interaction

Archive ouverte | Lehmann, Martin | CCSD

International audience. Virus assembly and interaction with host-cell proteins occur at length scales below the diffraction limit of visible light. Novel super-resolution microscopy techniques achieve nanometer reso...

Inhibition of HIV-1 Replication by Balsamin, a Ribosome Inactivating Protein of Momordica balsamina

Archive ouverte | Kaur, Inderdeep | CCSD

International audience. Ribosome-inactivating proteins (RIPs) are endowed with several medicinal properties, including antiviral activity. We demonstrate here that the recently identified type I RIP from Momordica b...

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