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Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions

Archive ouverte | Escudero, José Antonio | CCSD

International audience. Molecular examples of evolutionary innovation are scarce and generally involve point mutations. Innovation can occur through larger rearrangements, but here experimental data is extremely lim...

The Integron: Adaptation On Demand.

Archive ouverte | Escudero, José Antonio | CCSD

International audience. The integron is a powerful system which, by capturing, stockpiling, and rearranging new functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation capability in ch...

Chromosomal Integrons are Genetically and Functionally Isolated Units of Genomes

Archive ouverte | Blanco, Paula | CCSD

Integrons are genetic elements that increase the evolvability of bacteria by capturing new genes and stockpiling them in arrays. Sedentary chromosomal integrons (SCIs), can be massive and highly stabilized structures encoding hund...

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