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High glutathionylation of placental endothelial nitric oxide synthase in preeclampsia

Archive ouverte | Guerby, Paul | CCSD

International audience. Decreased nitric oxide (NO) bioavailability plays a critical role in the pathophysiology of preeclampsia (PE). Recent evidence indicates that S-glutathionylation may occur on the endothelial ...

Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

Archive ouverte | Guerby, Paul | CCSD

International audience. Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset gestational hypertension with (or without) proteinuria or end-organ failure, exclusively observed in humans...

A role for 4-hydroxy-2-nonenal in premature placental senescence in preeclampsia and intrauterine growth restriction

Archive ouverte | Tasta, Oriane | CCSD

International audience. Premature placental senescence is a hallmark of pregnancy-related disorders such as intrauterine growth restriction (IUGR) and preeclampsia (PE), two major cause of maternal and neonatal morb...

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