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Transketolase of Staphylococcus aureus in the Control of Master Regulators of Stress Response During Infection

Archive ouverte | Tan, Xin | CCSD

International audience. Staphylococcus aureus is a leading cause of both acute and chronic infections in humans. The importance of the pentose phosphate pathway (PPP) during S. aureus infection is currently largely ...

Chronic Staphylococcus aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence

Archive ouverte | Tan, Xin | CCSD

International audience. Background: Chronic lung infection in cystic fibrosis (CF) patients by Staphylococcus aureus is a well-established epidemiological fact. Indeed, S. aureus is the most commonly identified path...

Lung-Adapted Staphylococcus aureus Isolates With Dysfunctional Agr System Trigger a Proinflammatory Response

Archive ouverte | Ramond, Elodie | CCSD

International audience. Background Staphylococcus aureus dominates the lung microbiota of children with cystic fibrosis (CF) and persistent clones are able to establish chronic infection for years, having a direct d...

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