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Essential and recurrent roles for hairpin RNAs in silencing de novo sex chromosome conflict in Drosophila simulans

Archive ouverte | Vedanayagam, Jeffrey | CCSD

International audience. Meiotic drive loci distort the normally equal segregation of alleles, which benefits their own transmission even in the face of severe fitness costs to their host organism. However, relativel...

Epigenetic maintenance of telomere identity in Drosophila: buckle up for the sperm ride.

Archive ouverte | Dubruille, Raphaëlle | CCSD

International audience. A critical function of telomeres is to prevent the ligation of chromosome ends by DNA repair enzymes. In most eukaryotes, telomeric DNA consists in large arrays of G-rich tandem repeats that ...

Distinct spermiogenic phenotypes underlie sperm elimination in the Segregation Distorter meiotic drive system

Archive ouverte | Herbette, Marion | CCSD

International audience. Segregation Distorter (SD) is a male meiotic drive system in Drosophila melanogaster. Males heterozygous for a selfish SD chromosome rarely transmit the homologous SD + chromosome. It is well...

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