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Structural Insight into the Mycobacterium tuberculosis Rv0020c Protein and Its Interaction with the PknB Kinase

Archive ouverte | Roumestand, Christian | CCSD

International audience. The protein Rv0020c from Mycobacterium tuberculosis, also called FhaA, is one of the major substrates of the essential Ser/Thr protein kinase (STPK) PknB. The protein is composed of three dom...

The Mycobacterium tuberculosis Ser/Thr kinase substrate Rv2175c is a DNA-binding protein regulated by phosphorylation.

Archive ouverte | Cohen-Gonsaud, Martin | CCSD

International audience. Recent efforts have underlined the role of serine/threonine protein kinases in growth, pathogenesis, and cell wall metabolism in Mycobacterium tuberculosis. Although most kinases have been in...

Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism.

Archive ouverte | Barthe, Philippe | CCSD

International audience. The OdhI protein is key regulator of the TCA cycle in Corynebacterium glutamicum. This highly conserved protein is found in GC rich Gram-positive bacteria (e.g., the pathogenic Mycobacterium ...

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