Suggestions

Du même auteur

Intercalated Cell Depletion and Vacuolar H + -ATPase Mistargeting in an Ae1 R607H Knockin Model

Archive ouverte | Mumtaz, Rizwan | CCSD

International audience. Distal nephron acid secretion is mediated by highly specialized type A intercalated cells (A-ICs), which contain vacuolar H+-ATPase (V-type ATPase)-rich vesicles that fuse with the apical pla...

Renal proximal tubules are sensitive to metabolic acidosis

Archive ouverte | Hennings, J. Christopher | CCSD

Abstract Patients suffering from distal renal tubular acidosis (dRTA) are sometimes diagnosed with proximal tubule dysfunction with leaks of phosphate, uric acid, amino acids, and low-molecular-weight proteins, also known as Fanco...

Analysis of CLCNKB mutations at dimer‐interface, calcium‐binding site, and pore reveals a variety of functional alterations in ClC‐Kb channel leading to Bartter syndrome

Archive ouverte | Bignon, Yohan | CCSD

International audience. Pathological missense mutations in CLCNKB gene give a wide spectrum of clinical phenotypes in Bartter syndrome type III patients. Molecular analysis of the mutated ClC-Kb channels can be help...

Chargement des enrichissements...