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A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: a potential link between signal transduction and RNA stability

Archive ouverte | Gallouzi, I. E. | CCSD

International audience. A potential p120 GTPase-activating protein (RasGAP) effector, G3BP (RasGAP Src homology 3 [SH3] binding protein), was previously identified based on its ability to bind the SH3 domain of RasG...

The RasGAP-associated endoribonuclease G3BP assembles stress granules

Archive ouverte | Tourriere, H. | CCSD

International audience. Stress granules (SGs) are formed in the cytoplasm in response to various toxic agents, and are believed to play a critical role in the regulation of mRNA metabolism during stress. In SGs, mRN...

Control of fetal growth and neonatal survival by the RasGAP-associated endoribonuclease G3BP

Archive ouverte | Zekri, L. | CCSD

International audience

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