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The retinoblastoma protein is essential for cyclin A repression in quiescent cells

Archive ouverte | Philips, A. | CCSD

International audience. Cyclin A is a positive regulatory component of kinases required for the progression through S phase and for the transition between the G2 and M phases of the cell division cycle. Previous stu...

Cyclin A expression is under negative transcriptional control during the cell cycle

Archive ouverte | Huet, X. | CCSD

International audience. Transcription of the gene coding for cyclin A, a protein required for S-phase transit, is cell cycle regulated and is restricted to proliferating cells. To further explore transcriptional reg...

Relief of cyclin A gene transcriptional inhibition during activation of human primary T lymphocytes via CD2 and CD28 adhesion molecules

Archive ouverte | Plet, A. | CCSD

International audience. Cyclin A transcription is cell cycle regulated and induced by cell proliferative signals. To understand the mechanisms underlined in this regulation in normal human cells, we have analysed in...

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