An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

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Blein, S. | Bardel, Claire | Danjean, V. | Mcguffog, L. | Healey, S. | Barrowdale, D. | Lee, A. | Dennis, J. | Kuchenbaecker, K. B. | Soucy, P. | Terry, M. B. | Chung, W. K. | Goldgar, D. E. | Buys, S. S. | Janavicius, R. | Tihomirova, L. | Tung, N. | Dorfling, C. M. | Rensburg, E. J., Van | Neuhausen, S. L. | Ding, Y. C. | Gerdes, A. M. | Ejlertsen, B. | Nielsen, F. C. | Hansen, T. V. | Osorio, A. | Benitez, J. | Conejero, R. A. | Segota, E. | Weitzel, J. N. | Thelander, M. | Peterlongo, P. | Radice, P. | Pensotti, V. | Dolcetti, R. | Bonanni, B. | Peissel, B. | Zaffaroni, D. | Scuvera, G. | Manoukian, S. | Varesco, L. | Capone, G. L. | Papi, L. | Ottini, L. | Yannoukakos, D. | Konstantopoulou, I. | Garber, J. | Hamann, U. | Donaldson, A. | Brady, A. | Brewer, C. | Foo, C. | Evans, D. G. | Frost, D. | Eccles, D. | Douglas, F. | Cook, J. | Adlard, J. | Barwell, J. | Walker, L. | Izatt, L. | Side, L. E. | Kennedy, M. J. | Tischkowitz, M. | Rogers, M. T. | Porteous, M. E. | Morrison, P. J. | Platte, R. | Eeles, R. | Davidson, R. | Hodgson, S. | Cole, T. | Godwin, A. K. | Isaacs, C. | Claes, K. | de Leeneer, K. | Meindl, A. | Gehrig, A. | Wappenschmidt, B. | Sutter, C. | Engel, C. | Niederacher, D. | Steinemann, D. | Plendl, H. | Kast, K. | Rhiem, K. | Ditsch, N. | Arnold, N. | Varon-Mateeva, R. | Schmutzler, R. K. | Preisler-Adams, S. | Markov, N. B. | Wang-Gohrke, S. | Pauw, A., De | Lefol, C. | Lasset, Christine | Leroux, D. | Rouleau, E. | Damiola, F. | Bonadona, V.

Edité par CCSD ; BioMed Central -

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Background Germline mutations in the BRCA1 and BRCA2 genes are associated with increased risks of breast and ovarian cancers. Although several common variants have been associated with breast cancer susceptibility in mutation carr...

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