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A multicenter randomized controlled trial of a 3-L/kg/min versus 2-L/kg/min high-flow nasal cannula flow rate in young infants with severe viral bronchiolitis (TRAMONTANE 2)

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Milesi, Christophe | Pierre, Anne-Florence | Deho, Anna | Pouyau, Robin | Liet, Jean-Michel | Guillot, Camille | Guilbert, Anne-Sophie | Rambaud, Jérôme | Millet, Astrid | Afanetti, Mickael | Guichoux, Julie | Genuini, Mathieu | Mansir, Thierry | Bergounioux, Jean | Michel, Fabrice | Marcoux, Marie-Odile | Baleine, Julien | Durand, Sabine | Durand, Philippe | Dauger, Stéphane | Javouhey, Etienne | Leteurtre, Stéphane | Brissaud, Olivier | Renolleau, Sylvain | Portefaix, Aurélie | Douillard, Aymeric | Cambonie, Gilles | For The Gfrup Respiratory Study Group, For The Gfrup Respiratory Study Group

Edité par CCSD ; Springer Verlag -

High-flow nasal cannula (HFNC) therapy is increasingly proposed as first-line respiratory support for infants with acute viral bronchiolitis (AVB). Most teams use 2 L/kg/min, but no study compared different flow rates in this setting. We hypothesized that 3 L/kg/min would be more efficient for the initial management of these patients.

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