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A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation

Archive ouverte | Boul, Manon | CCSD

International audience. Abstract The development of livers-on-a-chip aims to provide pharmaceutical companies with reliable systems to perform drug screening and toxicological studies. To that end, microfluidic syst...

On‐Chip Differentiation of Hepatic Cords with Radial Flow

Archive ouverte | Rajendran, Alan Raj Jeffrey | CCSD

International audience. Due to a more physiological reproduction of the in vivo situation, liver‐on‐a‐chip devices in recent studies have shown higher sensitivity and accuracy for hepatotoxicity testing compared to ...

GDF15 secreted by senescent endothelial cells improves vascular progenitor cell functions

Archive ouverte | Ha, Guillaume | CCSD

International audience. Endothelial dysfunction (ED) is part of the first steps in the development of cardiovascular diseases (CVD). Growth Differentiation Factor 15 (GDF15) is a cytokine belonging to the Transformi...

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